Ketamine: A Transformational Catalyst
Review of The Ketamine Papers: Science, Therapy, and Transformation edited by Phil Wolfson, M.D., and Glenn Hartelius, Ph.D.
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PHIL WOLFSON, M.D., AND GLENN HARTELIUS, PH.D., have edited a new book en- titled, The Ketamine Papers: Science,Therapy, and Transformation, published by the Mul- tidisciplinary Association for Psychedelic Studies (MAPS). Ketamine is a Schedule 3 prescription drug that has been safely used in anesthesia for decades. Many years ago, it was discovered that as anesthesia wore off, patients were having unique and often disturbing psychedelic effects for which they were unprepared.These effects were dubbed an “emergent syndrome.”This propensity of ketamine to occasion psychedelic experiences was pursued and used in psychedelic psychotherapy following the lead of the Mexican psychiatrist Salvador Roquet. In one of the many illuminating chapters of The Ketamine Papers, Richard Yensen recounts his direct experience with Roquet’s methods and describes their evolution in psychedelic practice.
With the familiarity that arises from widespread applications, anecdotal informa- tion indicated that ketamine produces relief from depression.This was pursued in the late 1990s and thereafter by researchers at the National Institute of Mental Health, who made every effort by reducing dosage to exclude the psychedelic effects but still produce an antidepressant response.
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