SPRAVATO® is a prescription medicine, used along with an antidepressant taken by mouth, to treat:
Adults with treatment-resistant depression (TRD)
Depressive symptoms in adults with major depressive disorder (MDD) with suicidal thoughts or actions
How does SPRAVATO®Work?
SPRAVATO® targets the N-methyl-D-aspartate (NMDA) receptor and is believed to work differently than currently available oral antidepressants. The exact way that SPRAVATO® works is unknown.
HOW OFTEN WILL I RECEIVE TREATMENT?
ADULTS WITH TREATMENT-RESISTANT DEPRESSION (TRD)
WEEKS 1-4 Twice weekly WEEKS 5-8 Once weekly WEEKS 5-8 Once every week or two
DEPRESSIVE SYMPTOMS IN ADULTS WITH MAJOR DEPRESSIVE DISORDER
FOUR WEEKS Twice weekly
Depending on which treatment you receive, you and your healthcare provider will determine if continued treatment with SPRAVATO® is necessary.
What to Expect During your SPRAVATO® Treatment
You will not be able to drive, so you will need to plan transportation for treatment days.
You will administer the nasal spray yourself under the supervision of a healthcare provider.
You'll be monitored for side effects for at least two hours.
Your healthcare provider will tell you when it's OK to leave.
Do not drive, operate machinery or do anything where you need to be completely alert until the day after a treatment session, following a restful sleep.
SCHEDULE AN APPOINTMENT WITH ONE OF OUR PROVIDERS TO SEE IF THIS TREATMENT MAY BE RIGHT FOR YOU.
Feel like yourself again. SPRAVATO®, the only FDA-approved nasal spray for adults with treatment-resistant depression, reduces depression symptoms when two or more oral antidepressants haven’t worked. SPRAVATO® can be taken with or without an oral antidepressant.
What is SPRAVATO® (esketamine) CIII nasal spray? SPRAVATO® is a prescription medicine used with an antidepressant taken by mouth to treat: Depressive symptoms in adults with major depressive disorder (MDD) with suicidal thoughts or actions SPRAVATO® is not for use as a medicine to prevent or relieve pain (anesthetic). It is not known if SPRAVATO® is safe or effective as an anesthetic medicine. It is not known if SPRAVATO® is safe and effective for use in preventing suicide or in reducing suicidal thoughts or actions. SPRAVATO® is not for use in place of hospitalization if your healthcare provider determines that hospitalization is needed, even if improvement is experienced after the first dose of SPRAVATO®. It is not known if SPRAVATO® is safe and effective in children.
